BDBM227902 4-[(2-Fluoro-5-hydroxy-4-methylphenyl)amino]-8-{[4-(2-hydroxyethyl)piperidin-1-yl]methyl}-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepin-5-one::US10047096, 163

SMILES Cc1cc(F)c(Nc2ccnc3Nc4ccc(CN5CCC(CCO)CC5)cc4NC(=O)c23)cc1O

InChI Key InChIKey=DPRXHQKZIFLCDL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 227902   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227902(4-[(2-Fluoro-5-hydroxy-4-methylphenyl)amino]-8-{[4...)
Affinity DataIC50:  0.388nMpH: 7.0Assay Description:The kinase used was a recombinant fusion protein composed of N-terminal GST and a C-terminal fragment of human KDR (amino acids D807-V1356), expresse...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent